Emergency Contraceptive Selector
When you hear the name I-Pill, think of a quick, over‑the‑counter option for emergency contraception.
What Is the I-Pill (Levonorgestrel)?
I-Pill (Levonorgestrel) is a single‑dose emergency contraceptive pill containing 1.5 mg of levonorgestrel, approved for use up to 72 hours after unprotected sex. It is marketed in the United States as an over‑the‑counter product, though some states still require proof of age. Levonorgestrel works by postponing ovulation and, if fertilisation has already happened, it may interfere with implantation. The pill is most effective when taken as soon as possible after the incident.
Why Compare Alternatives?
Choosing the right emergency contraceptive depends on timing, medical history, cost, and personal preference. Not every brand works the same way, and some options are prescription‑only. By lining up the key features side by side, you can see which fits your situation best.
Major Alternatives on the Market
Below are the most common non‑prescription or prescription alternatives to the I‑Pill:
- Plan B One‑Step - another levonorgestrel‑based pill, often priced slightly higher.
- Ulipristal acetate - sold under the brand name Ella, a prescription‑only pill that remains effective up to 120 hours.
- Copper IUD (Paragard) - the most effective long‑term method, insertable up to five days after intercourse.
- Yuzpe regimen - a combination of estrogen and progestin tablets taken in two doses, often used when other options are unavailable.
Head‑to‑Head Comparison Table
Product | Efficacy (≈ % pregnancy prevention) | Window of Use | Prescription Needed? | Typical Cost (US$) | Common Side Effects |
---|---|---|---|---|---|
I‑Pill (Levonorgestrel) | 85‑89 | 0‑72 h | No | 30‑45 | Nausea, fatigue, headache |
Plan B One‑Step | 82‑86 | 0‑72 h | No | 35‑50 | Similar to I‑Pill |
Ulipristal acetate (Ella) | 95‑98 | 0‑120 h | Yes | 45‑60 | Headache, dizziness, abdominal pain |
Copper IUD (Paragard) | 99+ | 0‑120 h (insertable up to 5 days) | Yes | 800‑1000 (includes insertion) | Cramping, heavier periods |
Yuzpe regimen | 73‑85 | 0‑72 h | No (uses OTC pills) | 5‑15 (depends on available pills) | Nausea, vomiting, menstrual changes |
How Timing Affects Each Option
Levonorgestrel pills, including the I‑Pill, lose potency quickly after the 72‑hour mark. Ulipristal acetate’s advantage is a slower decline in effectiveness, making it a safer bet if you’re beyond the three‑day window but still within five days.
The copper IUD is unique because it offers a physical barrier that prevents fertilisation and can be left in place for up to ten years. However, it requires a trained clinician for insertion, so rapid access isn’t always guaranteed.

Prescription vs. Over‑the‑Counter: What That Means for You
In most U.S. states, both I‑Pill and Plan B are available without a prescription, though minors may need parental consent in a few places. Ulipristal acetate and the copper IUD demand a prescription, meaning you’ll need to visit a clinic or pharmacy that can write one. The Yuzpe regimen uses regular combined oral contraceptive pills, which are prescription‑only in the U.S., but many people already have them on hand for regular birth control.
Cost Considerations and Insurance Coverage
Insurance plans are more likely to cover prescription‑only options like ulipristal acetate and the copper IUD, especially if you have a preventive health plan. Over‑the‑counter products are paid out‑of‑pocket, but many pharmacies offer discount cards that can lower the price to under $20 per pack.
Side Effects: What to Expect
All hormonal emergency contraceptives share some common side effects: brief nausea, a slight drop in estrogen may cause spotting, and you might feel a bit tired. The copper IUD can cause cramping after insertion and heavier menstrual bleeding for a few cycles, which is a trade‑off for its high efficacy.
Special Populations and Contra‑Indications
Women who are pregnant, have a known allergy to levonorgestrel, or have severe liver disease should avoid hormonal pills. Ulipristal acetate isn’t recommended for women taking medications that induce liver enzymes (like some anticonvulsants), as these can lower its effectiveness.
People with copper‑sensitivity or Wilson’s disease should not use a copper IUD. The Yuzpe regimen may not be suitable for those with a history of blood clots due to the estrogen component.

How to Choose the Right Option for You
Ask yourself these quick questions:
- How many hours have passed since unprotected intercourse?
- Do you have a prescription ready, or can you get to a pharmacy today?
- Are you comfortable with a short‑term hormonal pill, or would you prefer a long‑term device?
- What is your budget for this one‑time need?
If you’re within 72 hours and need an easy, over‑the‑counter solution, the I‑Pill remains a solid choice. If you’re closer to the five‑day mark, ulipristal acetate gives you a better safety net. When you want both emergency protection and long‑term contraception, the copper IUD tops the list.
Practical Tips for Using Emergency Contraceptives
- Take the pill as soon as you can; delays lower effectiveness.
- If you vomit within two hours of swallowing, consult a pharmacist about a repeat dose.
- Follow up with a regular birth‑control method; emergency pills are not meant for ongoing use.
- Consider a pregnancy test if your next period is more than a week late.
Frequently Asked Questions
Can the I‑Pill be taken after 72 hours?
Effectiveness drops sharply after the three‑day window, and the FDA does not recommend use beyond 72 hours. For later timing, ulipristal acetate or a copper IUD are better options.
Do I need a prescription for any emergency contraceptive?
Levonorgestrel‑based pills (I‑Pill, Plan B) are OTC in most places. Ulipristal acetate and the copper IUD require a prescription, while the Yuzpe regimen uses prescription birth‑control pills you may already have.
Is the copper IUD a good emergency option for teenagers?
Many clinicians recommend it for teens because it provides immediate emergency protection and long‑term contraception, but insertion requires a visit to a qualified provider and parental consent laws vary by state.
What side effects are most common with ulipristal acetate?
Headache, dizziness, abdominal cramping, and occasional nausea are reported. Severe allergic reactions are rare but require immediate medical attention.
Can I use more than one emergency contraceptive at the same time?
Using two hormonal pills isn’t recommended because it can increase side‑effects without added benefit. If the first method fails (e.g., vomiting), a repeat dose of the same pill is advised rather than a different product.
Bottom Line
Each emergency contraceptive has a niche where it shines. The I‑Pill offers quick, easy access for most users within three days. Ulipristal acetate steps in when you need a longer window, and the copper IUD provides the highest efficacy plus years of protection. Knowing the trade‑offs-timing, cost, prescription needs, and side‑effects-helps you pick the one that fits your life at that moment.
Caroline Keller
October 19, 2025 AT 14:14I feel like the I‑Pill is the unsung hero for anyone who panics after a night out.
It’s over‑the‑counter, so no doctor’s office is needed when you’re already stressed.
The 85‑89% efficacy is solid for a 72‑hour window.
Side effects are mild, usually a quick nausea that passes.
And it costs far less than a copper IUD, making it accessible for most budgets.
Bottom line: when you’re in a hurry, the I‑Pill gets the job done.