Sildenafil – Complete Guide

When working with Sildenafil, a prescription medication used to treat erectile dysfunction by increasing blood flow to the penis. Also known as Viagra, it works by inhibiting the enzyme phosphodiesterase type 5.

Understanding erectile dysfunction, the inability to achieve or maintain an erection sufficient for sexual activity. Also called ED, it can stem from physical, psychological, or lifestyle factors. Because Sildenafil directly targets the physiological cause, it is often the first line of treatment for men whose ED stems from vascular issues or medication side‑effects. If the problem is primarily psychological, doctors may combine therapy with the drug for better outcomes.

How Sildenafil Fits Into the PDE5 Inhibitor Class

PDE5 inhibitors, a drug class that includes Sildenafil, tadalafil and vardenafil, which block the enzyme phosphodiesterase type 5. Also known as penile vasodilators, they help relax smooth muscle in the penis, allowing blood to fill the erectile tissue. All members share the same core mechanism, but they differ in onset time, duration, and dosing schedule. For example, tadalafil can last up to 36 hours, while Sildenafil typically works for 4‑6 hours. Knowing these nuances helps patients pick the right option for their lifestyle.

Dosage is another key attribute. The usual starting dose for most men is 50 mg taken about an hour before sexual activity, with the possibility to adjust to 25 mg or 100 mg based on effectiveness and tolerance. The drug should be taken on an empty stomach because high‑fat meals can delay absorption. Timing, food, and alcohol consumption all influence how quickly the medication works, which is why doctors stress consistent habits when using it.

Interactions matter a lot, especially with cardiovascular conditions. cardiovascular disease, any disorder of the heart and blood vessels, such as coronary artery disease or hypertension. Also referred to as CVD, it is a key consideration when prescribing Sildenafil. The drug should never be combined with nitrates (often used for chest pain) because the combined effect can cause a dangerous drop in blood pressure. Patients with unstable heart disease, recent heart attacks, or severe low blood pressure are usually advised against using it.

Safety extends to where you buy it. Online pharmacies can offer convenience and lower prices, but only reputable, licensed sources should be used. Look for pharmacies that require a prescription, display a valid Canadian pharmacy license, and provide clear contact information. Generic versions of Sildenafil have the same active ingredient and are clinically equivalent, but cheaper price tags can tempt shoppers into shady sites. Always verify the authenticity of the medication to avoid counterfeit products that might lack the correct dosage or contain harmful contaminants.

Below you’ll find a curated collection of articles that dive deeper into each of these topics. Whether you’re curious about dosing strategies, need to understand drug interactions, or want tips on safe online purchasing, the posts following this intro cover the full spectrum of information you’ll need to use Sildenafil responsibly and effectively.